PDB 5lgu

PDB Information

PDB5LGU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
Vianello, P., Sartori, L., Amigoni, F., Cappa, A., Faga, G., Fattori, R., Legnaghi, E., Ciossani, G., Mattevi, A., Meroni, G., Moretti, L., Cecatiello, V., Pasqualato, S., Romussi, A., Thaler, F., Trifiro, P., Villa, M., Botrugno, O.A., Dessanti, P., Minucci, S., Vultaggio, S., Zagarri, E., Varasi, M., Mercurio, C.
J. Med. Chem.
HeaderOxidoreductase
Released2016-07-08
Resolution3.200
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5lguA01 14 May, 2017 1.10.10.10 Assigned
5lguA02 14 May, 2017 Holding pen
5lguA03 14 May, 2017 1.10.287.80 Assigned
5lguB00 14 May, 2017 1.20.58.1880 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UKL0 RCOR1_HUMAN Homo sapiens REST corepressor 1
O60341 KDM1A_HUMAN Homo sapiens Lysine-specific histone demethylase 1A