PDB 5ley

PDB Links
Overview

PDB Information

PDB	5LEY
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Schrader, J., Henneberg, F., Mata, R.A., Tittmann, K., Schneider, T.R., Stark, H., Bourenkov, G., Chari, A. Science
Header	Hydrolase
Released	2016-06-30
Resolution	1.900
CATH Insert Date	04 Sep, 2016

PDB Images (57)

5ley

PDB 5ley

5leya

PDB Chain 5leya

5leyA

PDB Chain 5leyA

5leyb

PDB Chain 5leyb

5leyB

PDB Chain 5leyB

5leyC

PDB Chain 5leyC

5leyD

PDB Chain 5leyD

5leyE

PDB Chain 5leyE

5leyF

PDB Chain 5leyF

5leyG

PDB Chain 5leyG

5leyH

PDB Chain 5leyH

5leyI

PDB Chain 5leyI

5leyJ

PDB Chain 5leyJ

5leyK

PDB Chain 5leyK

5leyL

PDB Chain 5leyL

5leyM

PDB Chain 5leyM

5leyN

PDB Chain 5leyN

5leyO

PDB Chain 5leyO

5leyP

PDB Chain 5leyP

5leyQ

PDB Chain 5leyQ

5leyR

PDB Chain 5leyR

5leyS

PDB Chain 5leyS

5leyT

PDB Chain 5leyT

5leyU

PDB Chain 5leyU

5leyV

PDB Chain 5leyV

5leyW

PDB Chain 5leyW

5leyX

PDB Chain 5leyX

5leyY

PDB Chain 5leyY

5leyZ

PDB Chain 5leyZ

5leya00

CATH Domain 5leya00

5leyA00

CATH Domain 5leyA00

5leyb00

CATH Domain 5leyb00

5leyB00

CATH Domain 5leyB00

5leyC00

CATH Domain 5leyC00

5leyD00

CATH Domain 5leyD00

5leyE00

CATH Domain 5leyE00

5leyF00

CATH Domain 5leyF00

5leyG00

CATH Domain 5leyG00

5leyH00

CATH Domain 5leyH00

5leyI00

CATH Domain 5leyI00

5leyJ00

CATH Domain 5leyJ00

5leyK00

CATH Domain 5leyK00

5leyL00

CATH Domain 5leyL00

5leyM00

CATH Domain 5leyM00

5leyN00

CATH Domain 5leyN00

5leyO00

CATH Domain 5leyO00

5leyP00

CATH Domain 5leyP00

5leyQ00

CATH Domain 5leyQ00

5leyR00

CATH Domain 5leyR00

5leyS00

CATH Domain 5leyS00

5leyT00

CATH Domain 5leyT00

5leyU00

CATH Domain 5leyU00

5leyV00

CATH Domain 5leyV00

5leyW00

CATH Domain 5leyW00

5leyX00

CATH Domain 5leyX00

5leyY00

CATH Domain 5leyY00

5leyZ00

CATH Domain 5leyZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	05 Sep, 2016	Chopped
A	05 Sep, 2016	Chopped
b	05 Sep, 2016	Chopped
B	05 Sep, 2016	Chopped
C	05 Sep, 2016	Chopped
D	05 Sep, 2016	Chopped
E	05 Sep, 2016	Chopped
F	05 Sep, 2016	Chopped
G	05 Sep, 2016	Chopped
H	05 Sep, 2016	Chopped
I	05 Sep, 2016	Chopped
J	05 Sep, 2016	Chopped
K	05 Sep, 2016	Chopped
L	05 Sep, 2016	Chopped
M	05 Sep, 2016	Chopped
N	05 Sep, 2016	Chopped
O	05 Sep, 2016	Chopped
P	05 Sep, 2016	Chopped
Q	05 Sep, 2016	Chopped
R	05 Sep, 2016	Chopped
S	05 Sep, 2016	Chopped
T	05 Sep, 2016	Chopped
U	05 Sep, 2016	Chopped
V	05 Sep, 2016	Chopped
W	05 Sep, 2016	Chopped
X	05 Sep, 2016	Chopped
Y	05 Sep, 2016	Chopped
Z	05 Sep, 2016	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5leya00	09 Sep, 2016	3.60.20.10	Assigned
5leyA00	09 Sep, 2016	3.60.20.10	Assigned
5leyb00	20 Oct, 2016	3.60.20.10	Assigned
5leyB00	09 Sep, 2016	3.60.20.10	Assigned
5leyC00	09 Sep, 2016	3.60.20.10	Assigned
5leyD00	09 Sep, 2016	3.60.20.10	Assigned
5leyE00	09 Sep, 2016	3.60.20.10	Assigned
5leyF00	09 Sep, 2016	3.60.20.10	Assigned
5leyG00	09 Sep, 2016	3.60.20.10	Assigned
5leyH00	09 Sep, 2016	3.60.20.10	Assigned
5leyI00	09 Sep, 2016	3.60.20.10	Assigned
5leyJ00	09 Sep, 2016	3.60.20.10	Assigned
5leyK00	09 Sep, 2016	3.60.20.10	Assigned
5leyL00	09 Sep, 2016	3.60.20.10	Assigned
5leyM00	09 Sep, 2016	3.60.20.10	Assigned
5leyN00	20 Oct, 2016	3.60.20.10	Assigned
5leyO00	09 Sep, 2016	3.60.20.10	Assigned
5leyP00	09 Sep, 2016	3.60.20.10	Assigned
5leyQ00	09 Sep, 2016	3.60.20.10	Assigned
5leyR00	09 Sep, 2016	3.60.20.10	Assigned
5leyS00	09 Sep, 2016	3.60.20.10	Assigned
5leyT00	09 Sep, 2016	3.60.20.10	Assigned
5leyU00	09 Sep, 2016	3.60.20.10	Assigned
5leyV00	09 Sep, 2016	3.60.20.10	Assigned
5leyW00	09 Sep, 2016	3.60.20.10	Assigned
5leyX00	09 Sep, 2016	3.60.20.10	Assigned
5leyY00	09 Sep, 2016	3.60.20.10	Assigned
5leyZ00	09 Sep, 2016	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25788	PSA3_HUMAN	Homo sapiens	Proteasome subunit alpha type-3
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P28066	PSA5_HUMAN	Homo sapiens	Proteasome subunit alpha type-5
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
O14818	PSA7_HUMAN	Homo sapiens	Proteasome subunit alpha type-7
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P60900	PSA6_HUMAN	Homo sapiens	Proteasome subunit alpha type-6
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
Q99436	PSB7_HUMAN	Homo sapiens	Proteasome subunit beta type-7
P49721	PSB2_HUMAN	Homo sapiens	Proteasome subunit beta type-2
P25786	PSA1_HUMAN	Homo sapiens	Proteasome subunit alpha type-1
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P28074	PSB5_HUMAN	Homo sapiens	Proteasome subunit beta type-5
P28072	PSB6_HUMAN	Homo sapiens	Proteasome subunit beta type-6
P28070	PSB4_HUMAN	Homo sapiens	Proteasome subunit beta type-4
P49720	PSB3_HUMAN	Homo sapiens	Proteasome subunit beta type-3
P25787	PSA2_HUMAN	Homo sapiens	Proteasome subunit alpha type-2
P25789	PSA4_HUMAN	Homo sapiens	Proteasome subunit alpha type-4
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1
P20618	PSB1_HUMAN	Homo sapiens	Proteasome subunit beta type-1