PDB 5l0k

PDB Information

PDB5L0K
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceRattus norvegicus
Primary Citation
Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design.
Jones, S.B., Pfeifer, L.A., Bleisch, T.J., Beauchamp, T.J., Durbin, J.D., Klimkowski, V.J., Hughes, N.E., Rito, C.J., Dao, Y., Gruber, J.M., Bui, H., Chambers, M.G., Chandrasekhar, S., Lin, C., McCann, D.J., Mudra, D.R., Oskins, J.L., Swearingen, C.A., Thirunavukkarasu, K., Norman, B.H.
Acs Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-07-27
Resolution2.730
CATH Insert Date14 Aug, 2016

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped
B 15 Aug, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5l0kA01 01 Sep, 2016 Holding pen
5l0kA02 01 Sep, 2016 4.10.410.20 Assigned
5l0kA03 01 Sep, 2016 3.40.720.10 Assigned
5l0kA04 01 Sep, 2016 3.40.570.10 Assigned
5l0kB01 01 Sep, 2016 Holding pen
5l0kB02 01 Sep, 2016 4.10.410.20 Assigned
5l0kB03 01 Sep, 2016 3.40.720.10 Assigned
5l0kB04 01 Sep, 2016 3.40.570.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q64610 ENPP2_RAT Rattus norvegicus Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Q64610 ENPP2_RAT Rattus norvegicus Ectonucleotide pyrophosphatase/phosphodiesterase family member 2