PDB 5ku3

PDB Information

PDB5KU3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.
Crawford, T.D., Romero, F.A., Lai, K.W., Tsui, V., Taylor, A.M., de Leon Boenig, G., Noland, C.L., Murray, J., Ly, J., Choo, E.F., Hunsaker, T.L., Chan, E.W., Merchant, M., Kharbanda, S., Gascoigne, K.E., Kaufman, S., Beresini, M.H., Liao, J., Liu, W., Chen, K.X., Chen, Z., Conery, A.R., Cote, A., Jayaram, H., Jiang, Y., Kiefer, J.R., Kleinheinz, T., Li, Y., Maher, J., Pardo, E., Poy, F., Spillane, K.L., Wang, F., Wang, J., Wei, X., Xu, Z., Xu, Z., Yen, I., Zawadzke, L., Zhu, X., Bellon, S., Cummings, R., Cochran, A.G., Albrecht, B.K., Magnuson, S.
J. Med. Chem.
HeaderTransferase
Released2016-07-12
Resolution1.140
CATH Insert Date20 Nov, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5ku3A01 24 Nov, 2016 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4