PDB Information

PDB5KH5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Primary Citation
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
Concha, N., Huang, J., Bai, X., Benowitz, A., Brady, P., Grady, L.C., Kryn, L.H., Holmes, D., Ingraham, K., Jin, Q., Pothier Kaushansky, L., McCloskey, L., Messer, J.A., O'Keefe, H., Patel, A., Satz, A.L., Sinnamon, R.H., Schneck, J., Skinner, S.R., Summerfield, J., Taylor, A., Taylor, J.D., Evindar, G., Stavenger, R.A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-06-14
Resolution2.630
CATH Insert Date07 Aug, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped
B 08 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5kh5A00 01 Sep, 2016 3.40.1180.10 Assigned
5kh5B00 01 Sep, 2016 3.40.1180.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q97SR4 ISPT_STRPN Streptococcus pneumoniae TIGR4 Isoprenyl transferase
Q97SR4 ISPT_STRPN Streptococcus pneumoniae TIGR4 Isoprenyl transferase
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