PDB 5ke0

PDB Information

PDB5KE0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.
Lim, J., Kelley, E.H., Methot, J.L., Zhou, H., Petrocchi, A., Chen, H., Hill, S.E., Hinton, M.C., Hruza, A., Jung, J.O., Maclean, J.K., Mansueto, M., Naumov, G.N., Philippar, U., Raut, S., Spacciapoli, P., Sun, D., Siliphaivanh, P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-06-09
Resolution1.680
CATH Insert Date07 Aug, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ke0A01 01 Sep, 2016 3.30.200.20 Assigned
5ke0A02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P63086 MK01_RAT Rattus norvegicus Mitogen-activated protein kinase 1