PDB 5k9r

PDB Links
Overview

PDB Information

PDB	5K9R
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors. Meegalla, S.K., Huang, H., Illig, C.R., Parks, D.J., Chen, J., Lee, Y.K., Wilson, K.J., Patel, S.K., Cheung, W.S., Lu, T., Kirchner, T., Askari, H.B., Geisler, J., Patch, R.J., Gibbs, A.C., Rady, B., Connelly, M., Player, M.R. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-06-01
Resolution	2.700
CATH Insert Date	04 Sep, 2016

PDB Images (5)

Image of CATH 5k9r

5k9r

PDB 5k9r

Image of CATH 5k9rA

5k9rA

PDB Chain 5k9rA

Image of CATH 5k9rB

5k9rB

PDB Chain 5k9rB

Image of CATH 5k9rA00

5k9rA00

CATH Domain 5k9rA00

Image of CATH 5k9rB00

5k9rB00

CATH Domain 5k9rB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Sep, 2016	Chopped
B	05 Sep, 2016	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5k9rA00	08 Sep, 2016	1.10.1300.10	Assigned
5k9rB00	09 Sep, 2016	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A