PDB Information

PDB5K5N
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Liang, S.H., Chen, J.M., Normandin, M.D., Chang, J.S., Chang, G.C., Taylor, C.K., Trapa, P., Plummer, M.S., Para, K.S., Conn, E.L., Lopresti-Morrow, L., Lanyon, L.F., Cook, J.M., Richter, K.E., Nolan, C.E., Schachter, J.B., Janat, F., Che, Y., Shanmugasundaram, V., Lefker, B.A., Enerson, B.E., Livni, E., Wang, L., Guehl, N.J., Patnaik, D., Wagner, F.F., Perlis, R., Holson, E.B., Haggarty, S.J., El Fakhri, G., Kurumbail, R.G., Vasdev, N.
Angew.Chem.Int.Ed.Engl.
HeaderTransferase
Released2016-05-23
Resolution2.200
CATH Insert Date09 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5k5nA01 13 Oct, 2016 3.30.200.20 Assigned
5k5nA02 13 Oct, 2016 1.10.510.10 Assigned
5k5nB01 14 Oct, 2016 3.30.200.20 Assigned
5k5nB02 14 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta
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