PDB 5jsb

PDB Information

PDB5JSB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Berger, S., Procko, E., Margineantu, D., Lee, E.F., Shen, B.W., Zelter, A., Silva, D.A., Chawla, K., Herold, M.J., Garnier, J.M., Johnson, R., MacCoss, M.J., Lessene, G., Davis, T.N., Stayton, P.S., Stoddard, B.L., Fairlie, W.D., Hockenbery, D.M., Baker, D.
Elife
HeaderViral Protein/Inhibitor
Released2016-05-07
Resolution2.740
CATH Insert Date27 Nov, 2016

PDB Images (25)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 Nov, 2016 Chopped
B 28 Nov, 2016 Chopped
C 28 Nov, 2016 Chopped
D 28 Nov, 2016 Chopped
E 28 Nov, 2016 Chopped
F 28 Nov, 2016 Chopped
G 28 Nov, 2016 Chopped
H 28 Nov, 2016 Chopped
I 28 Nov, 2016 Chopped
J 28 Nov, 2016 Chopped
K 28 Nov, 2016 Chopped
L 28 Nov, 2016 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
5jsbA01 01 Dec, 2016 1.10.437.10 Assigned
5jsbB00 01 Dec, 2016 1.10.132.20 Assigned
5jsbC01 01 Dec, 2016 1.10.437.10 Assigned
5jsbD00 01 Dec, 2016 1.10.132.20 Assigned
5jsbE01 01 Dec, 2016 1.10.437.10 Assigned
5jsbF00 01 Dec, 2016 1.10.132.20 Assigned
5jsbG01 02 Dec, 2016 1.10.437.10 Assigned
5jsbH00 02 Dec, 2016 1.10.132.20 Assigned
5jsbI01 02 Dec, 2016 1.10.437.10 Assigned
5jsbJ00 02 Dec, 2016 1.10.132.20 Assigned
5jsbK01 01 Dec, 2016 1.10.437.10 Assigned
5jsbL00 01 Dec, 2016 1.10.132.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1