PDB 5jk7

PDB Information

PDB5JK7
MethodX-RAY DIFFRACTION
Host OrganismInsect cell expression vector pTIE1
Gene SourceHomo sapiens
Primary Citation
The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Wu, Y., Zhou, X., Barnes, C.O., DeLucia, M., Cohen, A.E., Gronenborn, A.M., Ahn, J., Calero, G.
Nat.Struct.Mol.Biol.
HeaderViral Protein/Dna Binding Protein
Released2016-04-26
Resolution3.490
CATH Insert Date16 Oct, 2016

PDB Images (23)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped
G 17 Oct, 2016 Chopped
H 17 Oct, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5jk7A01 01 Dec, 2017 2.130.10.10 Assigned
5jk7A02 01 Dec, 2017 2.130.10.10 Assigned
5jk7A03 01 Dec, 2017 2.130.10.10 Assigned
5jk7A04 01 Dec, 2017 1.10.150.910 Assigned
5jk7B01 15 Feb, 2018 2.130.10.10 Assigned
5jk7B02 15 Feb, 2018 2.130.10.10 Assigned
5jk7B03 15 Feb, 2018 2.130.10.10 Assigned
5jk7B04 15 Feb, 2018 1.10.150.910 Assigned
5jk7C00 28 Mar, 2018 2.130.10.10 Assigned
5jk7D00 21 Oct, 2016 3.40.470.10 Assigned
5jk7E00 28 Mar, 2018 2.130.10.10 Assigned
5jk7F00 16 Feb, 2017 1.20.5.4730 Assigned
5jk7G00 22 Oct, 2016 3.40.470.10 Assigned
5jk7H00 16 Feb, 2017 1.20.5.4730 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P13051 UNG_HUMAN Homo sapiens Uracil-DNA glycosylase
Q16531 DDB1_HUMAN Homo sapiens DNA damage-binding protein 1
Q9Y4B6 DCAF1_HUMAN Homo sapiens DDB1- and CUL4-associated factor 1
P12520 VPR_HV1N5 Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) Protein Vpr
Q16531 DDB1_HUMAN Homo sapiens DNA damage-binding protein 1
Q9Y4B6 DCAF1_HUMAN Homo sapiens DDB1- and CUL4-associated factor 1
P13051 UNG_HUMAN Homo sapiens Uracil-DNA glycosylase
P12520 VPR_HV1N5 Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) Protein Vpr