PDB Information

PDB5JHU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 1.
Cheruvallath, Z., Tang, M., McBride, C., Komandla, M., Miura, J., Ton-Nu, T., Erikson, P., Feng, J., Farrell, P., Lawson, J.D., Vanderpool, D., Wu, Y., Dougan, D.R., Plonowski, A., Holub, C., Larson, C.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-04-21
Resolution1.800
CATH Insert Date05 Jun, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jun, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5jhuA01 20 Jul, 2016 3.90.230.10 Assigned
5jhuA02 20 Jul, 2016 1.10.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P50579 MAP2_HUMAN Homo sapiens Methionine aminopeptidase 2