PDB Information

PDB5JC1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourcePlasmodium falciparum (isolate 3D7)
Primary Citation
Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin.
Sooriyaarachchi, S., Chofor, R., Risseeuw, M.D., Bergfors, T., Pouyez, J., Dowd, C.S., Maes, L., Wouters, J., Jones, T.A., Van Calenbergh, S., Mowbray, S.L.
Chemmedchem
HeaderOxidoreductase
Released2016-04-14
Resolution1.650
CATH Insert Date04 Sep, 2016

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Sep, 2016 Chopped
B 05 Sep, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5jc1A01 09 Sep, 2016 3.40.50.720 Assigned
5jc1A02 09 Sep, 2016 Holding pen
5jc1A03 09 Sep, 2016 1.10.1740.10 Assigned
5jc1B01 09 Sep, 2016 3.40.50.720 Assigned
5jc1B02 09 Sep, 2016 Holding pen
5jc1B03 09 Sep, 2016 1.10.1740.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8IKG4 DXR_PLAF7 Plasmodium falciparum 3D7 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
Q8IKG4 DXR_PLAF7 Plasmodium falciparum 3D7 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic