PDB 5ivt

PDB Information

PDB5IVT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Bungard, C.J., Williams, P.D., Ballard, J.E., Bennett, D.J., Beaulieu, C., Bahnck-Teets, C., Carroll, S.S., Chang, R.K., Dubost, D.C., Fay, J.F., Diamond, T.L., Greshock, T.J., Hao, L., Holloway, M.K., Felock, P.J., Gesell, J.J., Su, H.P., Manikowski, J.J., McKay, D.J., Miller, M., Min, X., Molinaro, C., Moradei, O.M., Nantermet, P.G., Nadeau, C., Sanchez, R.I., Satyanarayana, T., Shipe, W.D., Singh, S.K., Truong, V.L., Vijayasaradhi, S., Wiscount, C.M., Vacca, J.P., Crane, S.N., McCauley, J.A.
Acs Med.Chem.Lett.
HeaderHydrolase/Inhibitor
Released2016-03-21
Resolution1.150
CATH Insert Date29 May, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ivtA00 18 Jul, 2016 2.40.70.10 Assigned
5ivtB00 18 Jul, 2016 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
G0X8E8 G0X8E8_9HIV1 Human immunodeficiency virus 1 Pol protein
G0X8E8 G0X8E8_9HIV1 Human immunodeficiency virus 1 Pol protein