PDB 5ivq

PDB Information

PDB5IVQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Bungard, C.J., Williams, P.D., Ballard, J.E., Bennett, D.J., Beaulieu, C., Bahnck-Teets, C., Carroll, S.S., Chang, R.K., Dubost, D.C., Fay, J.F., Diamond, T.L., Greshock, T.J., Hao, L., Holloway, M.K., Felock, P.J., Gesell, J.J., Su, H.P., Manikowski, J.J., McKay, D.J., Miller, M., Min, X., Molinaro, C., Moradei, O.M., Nantermet, P.G., Nadeau, C., Sanchez, R.I., Satyanarayana, T., Shipe, W.D., Singh, S.K., Truong, V.L., Vijayasaradhi, S., Wiscount, C.M., Vacca, J.P., Crane, S.N., McCauley, J.A.
Acs Med.Chem.Lett.
HeaderHydrolase/Inhibitor
Released2016-03-21
Resolution1.570
CATH Insert Date29 May, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ivqA00 18 Jul, 2016 2.40.70.10 Assigned
5ivqB00 18 Jul, 2016 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q77VV3 Q77VV3_9HIV1 Human immunodeficiency virus 1 Protease
Q77VV3 Q77VV3_9HIV1 Human immunodeficiency virus 1 Protease