PDB Information

PDB5ITA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
An integrated model of RAF inhibitor action predicts inhibitor activity against oncogenic BRAF signaling
Karoulia, Z., Wu, Y., Ahmed, T.A., Qisheng, X., Bollard, J., Krepler, C., Wu, X., Zhang, C., Bollag, G., Herlym, M., Fagin, J.A., Lujambio, A., Gavathiotis, E., Poulikakos, P.I.
Cancer Cell
HeaderTransferase/Transferase Inhibitor
Released2016-03-16
Resolution1.950
CATH Insert Date14 Aug, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped
B 15 Aug, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5itaA01 01 Sep, 2016 3.30.200.20 Assigned
5itaA02 01 Sep, 2016 1.10.510.10 Assigned
5itaB01 01 Sep, 2016 3.30.200.20 Assigned
5itaB02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
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