PDB Information

PDB5IGK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.
Picaud, S., Leonards, K., Lambert, J.P., Dovey, O., Wells, C., Fedorov, O., Monteiro, O., Fujisawa, T., Wang, C.Y., Lingard, H., Tallant, C., Nikbin, N., Guetzoyan, L., Ingham, R., Ley, S.V., Brennan, P., Muller, S., Samsonova, A., Gingras, A.C., Schwaller, J., Vassiliou, G., Knapp, S., Filippakopoulos, P.
Sci Adv
HeaderTranscription
Released2016-02-28
Resolution1.700
CATH Insert Date06 Nov, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5igkA01 10 Nov, 2016 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4