PDB Information

PDB5I94
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and evaluation of novel glutaminase inhibitors.
McDermott, L.A., Iyer, P., Vernetti, L., Rimer, S., Sun, J., Boby, M., Yang, T., Fioravanti, M., O'Neill, J., Wang, L., Drakes, D., Katt, W., Huang, Q., Cerione, R.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-02-19
Resolution2.980
CATH Insert Date29 May, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped
C 30 May, 2016 Chopped
D 30 May, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5i94A01 17 Jul, 2016 1.10.238.210 Assigned
5i94A02 17 Jul, 2016 3.40.710.10 Assigned
5i94B01 17 Jul, 2016 1.10.238.210 Assigned
5i94B02 17 Jul, 2016 3.40.710.10 Assigned
5i94C01 17 Jul, 2016 1.10.238.210 Assigned
5i94C02 17 Jul, 2016 3.40.710.10 Assigned
5i94D01 17 Jul, 2016 1.10.238.210 Assigned
5i94D02 17 Jul, 2016 3.40.710.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O94925 GLSK_HUMAN Homo sapiens Glutaminase kidney isoform, mitochondrial
O94925 GLSK_HUMAN Homo sapiens Glutaminase kidney isoform, mitochondrial
O94925 GLSK_HUMAN Homo sapiens Glutaminase kidney isoform, mitochondrial
O94925 GLSK_HUMAN Homo sapiens Glutaminase kidney isoform, mitochondrial