PDB Information

PDB5I5Z
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19.
Mallinger, A., Schiemann, K., Rink, C., Sejberg, J., Honey, M.A., Czodrowski, P., Stubbs, M., Poeschke, O., Busch, M., Schneider, R., Schwarz, D., Musil, D., Burke, R., Urbahns, K., Workman, P., Wienke, D., Clarke, P.A., Raynaud, F.I., Eccles, S.A., Esdar, C., Rohdich, F., Blagg, J.
Acs Med.Chem.Lett.
HeaderTransferase
Released2016-02-15
Resolution2.600
CATH Insert Date24 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped
B 25 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5i5zA01 15 May, 2016 3.30.200.20 Assigned
5i5zA02 15 May, 2016 1.10.510.10 Assigned
5i5zB01 15 May, 2016 1.10.472.10 Assigned
5i5zB02 15 May, 2016 1.10.472.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49336 CDK8_HUMAN Homo sapiens Cyclin-dependent kinase 8
P24863 CCNC_HUMAN Homo sapiens Cyclin-C
CATH-Gene3D is a Global Biodata Core Resource Learn more...