PDB Information

PDB5HZN
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Identification of a 5-[3-phenyl-(2-cyclic-ether)-methylether]-4-aminopyrrolo[2,3-d]pyrimidine series of IGF-1R inhibitors.
Stauffer, F., Cowan-Jacob, S.W., Scheufler, C., Furet, P.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2016-02-02
Resolution2.200
CATH Insert Date17 Apr, 2016

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Chopped
D 18 Apr, 2016 Chopped
E 18 Apr, 2016 Chopped
F 18 Apr, 2016 Chopped
G 18 Apr, 2016 Chopped
H 18 Apr, 2016 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5hznA01 15 May, 2016 3.30.200.20 Assigned
5hznA02 15 May, 2016 1.10.510.10 Assigned
5hznB01 14 May, 2016 3.30.200.20 Assigned
5hznB02 14 May, 2016 1.10.510.10 Assigned
5hznC01 15 May, 2016 3.30.200.20 Assigned
5hznC02 15 May, 2016 1.10.510.10 Assigned
5hznD01 15 May, 2016 3.30.200.20 Assigned
5hznD02 15 May, 2016 1.10.510.10 Assigned
5hznE01 15 May, 2016 3.30.200.20 Assigned
5hznE02 15 May, 2016 1.10.510.10 Assigned
5hznF01 15 May, 2016 3.30.200.20 Assigned
5hznF02 15 May, 2016 1.10.510.10 Assigned
5hznG01 15 May, 2016 3.30.200.20 Assigned
5hznG02 15 May, 2016 1.10.510.10 Assigned
5hznH01 15 May, 2016 3.30.200.20 Assigned
5hznH02 15 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor