PDB Information

PDB5HVY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8.
Bergeron, P., Koehler, M.F., Blackwood, E.M., Bowman, K., Clark, K., Firestein, R., Kiefer, J.R., Maskos, K., McCleland, M.L., Orren, L., Ramaswamy, S., Salphati, L., Schmidt, S., Schneider, E.V., Wu, J., Beresini, M.
Acs Med.Chem.Lett.
HeaderTransferase/Transcription
Released2016-01-28
Resolution2.390
CATH Insert Date24 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped
B 25 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5hvyA01 14 May, 2016 3.30.200.20 Assigned
5hvyA02 14 May, 2016 1.10.510.10 Assigned
5hvyB01 14 May, 2016 1.10.472.10 Assigned
5hvyB02 14 May, 2016 1.10.472.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P24863 CCNC_HUMAN Homo sapiens Cyclin-C
P49336 CDK8_HUMAN Homo sapiens Cyclin-dependent kinase 8