PDB 5hni

PDB Links
Overview

PDB Information

PDB	5HNI
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844). Ugolini, A., Kenigsberg, M., Rak, A., Vallee, F., Houtmann, J., Lowinski, M., Capdevila, C., Khider, J., Albert, E., Martinet, N., Nemecek, C., Grapinet, S., Bacque, E., Roesner, M., Delaisi, C., Calvet, L., Bonche, F., Semiond, D., Egile, C., Goulaouic, H., Schio, L. J.Med.Chem.
Header	Transferase
Released	2016-01-18
Resolution	1.710
CATH Insert Date	04 Dec, 2016

PDB Images (7)

Image of CATH 5hni

5hni

PDB 5hni

Image of CATH 5hniX

5hniX

PDB Chain 5hniX

Image of CATH 5hniY

5hniY

PDB Chain 5hniY

Image of CATH 5hniX01

5hniX01

CATH Domain 5hniX01

Image of CATH 5hniX02

5hniX02

CATH Domain 5hniX02

Image of CATH 5hniY01

5hniY01

CATH Domain 5hniY01

Image of CATH 5hniY02

5hniY02

CATH Domain 5hniY02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
X	05 Dec, 2016	Chopped
Y	05 Dec, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hniX01	09 Dec, 2016	3.30.200.20	Assigned
5hniX02	09 Dec, 2016	1.10.510.10	Assigned
5hniY01	09 Dec, 2016	3.30.200.20	Assigned
5hniY02	09 Dec, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P08581	MET_HUMAN	Homo sapiens	Hepatocyte growth factor receptor
P08581	MET_HUMAN	Homo sapiens	Hepatocyte growth factor receptor