PDB 5hfu

PDB Links
Overview

PDB Information

PDB	5HFU
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors. Lin, H., Zeng, J., Xie, R., Schulz, M.J., Tedesco, R., Qu, J., Erhard, K.F., Mack, J.F., Raha, K., Rendina, A.R., Szewczuk, L.M., Kratz, P.M., Jurewicz, A.J., Cecconie, T., Martens, S., McDevitt, P.J., Martin, J.D., Chen, S.B., Jiang, Y., Nickels, L., Schwartz, B.J., Smallwood, A., Zhao, B., Campobasso, N., Qian, Y., Briand, J., Rominger, C.M., Oleykowski, C., Hardwicke, M.A., Luengo, J.I. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2016-01-07
Resolution	2.920
CATH Insert Date	10 Apr, 2016

PDB Images (11)

Image of CATH 5hfu

5hfu

PDB 5hfu

Image of CATH 5hfuA

5hfuA

PDB Chain 5hfuA

Image of CATH 5hfuB

5hfuB

PDB Chain 5hfuB

Image of CATH 5hfuA01

5hfuA01

CATH Domain 5hfuA01

Image of CATH 5hfuA02

5hfuA02

CATH Domain 5hfuA02

Image of CATH 5hfuA03

5hfuA03

CATH Domain 5hfuA03

Image of CATH 5hfuA04

5hfuA04

CATH Domain 5hfuA04

Image of CATH 5hfuB01

5hfuB01

CATH Domain 5hfuB01

Image of CATH 5hfuB02

5hfuB02

CATH Domain 5hfuB02

Image of CATH 5hfuB03

5hfuB03

CATH Domain 5hfuB03

Image of CATH 5hfuB04

5hfuB04

CATH Domain 5hfuB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hfuA01	21 Feb, 2018	3.40.367.20	Assigned
5hfuA02	21 Feb, 2018	3.30.420.40	Assigned
5hfuA03	21 Feb, 2018	3.40.367.20	Assigned
5hfuA04	21 Feb, 2018	3.30.420.40	Assigned
5hfuB01	21 Feb, 2018	3.40.367.20	Assigned
5hfuB02	21 Feb, 2018	3.30.420.40	Assigned
5hfuB03	21 Feb, 2018	3.40.367.20	Assigned
5hfuB04	21 Feb, 2018	3.30.420.40	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P52789	HXK2_HUMAN	Homo sapiens	Hexokinase-2
P52789	HXK2_HUMAN	Homo sapiens	Hexokinase-2