Structure-Based Design of an Iminoheterocyclic beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central A beta in Nonhuman Primates.
Mandal, M., Wu, Y., Misiaszek, J., Li, G., Buevich, A., Caldwell, J.P., Liu, X., Mazzola, R.D., Orth, P., Strickland, C., Voigt, J., Wang, H., Zhu, Z., Chen, X., Grzelak, M., Hyde, L.A., Kuvelkar, R., Leach, P.T., Terracina, G., Zhang, L., Zhang, Q., Michener, M.S., Smith, B., Cox, K., Grotz, D., Favreau, L., Mitra, K., Kazakevich, I., McKittrick, B.A., Greenlee, W., Kennedy, M.E., Parker, E.M., Cumming, J.N., Stamford, A.W.
J.Med.Chem.
