PDB 5hbh

PDB Links
Overview

PDB Information

PDB	5HBH
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. Mallinger, A., Schiemann, K., Rink, C., Stieber, F., Calderini, M., Crumpler, S., Stubbs, M., Adeniji-Popoola, O., Poeschke, O., Busch, M., Czodrowski, P., Musil, D., Schwarz, D., Ortiz-Ruiz, M.J., Schneider, R., Thai, C., Valenti, M., de Haven Brandon, A., Burke, R., Workman, P., Dale, T., Wienke, D., Clarke, P.A., Esdar, C., Raynaud, F.I., Eccles, S.A., Rohdich, F., Blagg, J. J.Med.Chem.
Header	Transferase
Released	2015-12-31
Resolution	2.500
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5hbh

5hbh

PDB 5hbh

Image of CATH 5hbhA

5hbhA

PDB Chain 5hbhA

Image of CATH 5hbhB

5hbhB

PDB Chain 5hbhB

Image of CATH 5hbhA01

5hbhA01

CATH Domain 5hbhA01

Image of CATH 5hbhA02

5hbhA02

CATH Domain 5hbhA02

Image of CATH 5hbhB01

5hbhB01

CATH Domain 5hbhB01

Image of CATH 5hbhB02

5hbhB02

CATH Domain 5hbhB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hbhA01	13 May, 2016	3.30.200.20	Assigned
5hbhA02	13 May, 2016	1.10.510.10	Assigned
5hbhB01	13 May, 2016	1.10.472.10	Assigned
5hbhB02	13 May, 2016	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C