PDB 5gwk

PDB Information

PDB5GWK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Wang, Y.R., Chen, S.F., Wu, C.C., Liao, Y.W., Lin, T.S., Liu, K.T., Chen, Y.S., Li, T.K., Chien, T.C., Chan, N.L.
Nucleic Acids Res.
HeaderIsomerase/Dna/Isomerase Inhibitor
Released2016-09-12
Resolution3.150
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Rejected
D 14 Nov, 2017 Rejected
E 14 Nov, 2017 Rejected
F 14 Nov, 2017 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5gwkA01 10 Dec, 2017 3.40.50.670 Assigned
5gwkA02 10 Dec, 2017 3.30.1490.30 Assigned
5gwkA03 10 Dec, 2017 3.90.199.10 Assigned
5gwkA04 10 Dec, 2017 3.30.1360.40 Assigned
5gwkA05 10 Dec, 2017 1.10.268.10 Assigned
5gwkB01 10 Dec, 2017 3.40.50.670 Assigned
5gwkB02 10 Dec, 2017 3.30.1490.30 Assigned
5gwkB03 10 Dec, 2017 3.90.199.10 Assigned
5gwkB04 10 Dec, 2017 3.30.1360.40 Assigned
5gwkB05 10 Dec, 2017 1.10.268.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11388 TOP2A_HUMAN Homo sapiens DNA topoisomerase 2-alpha
P11388 TOP2A_HUMAN Homo sapiens DNA topoisomerase 2-alpha