PDB 5gty

PDB Information

PDB5GTY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode.
Hu, C., Wang, A., Wu, H., Qi, Z., Li, X., Yan, X.E., Chen, C., Yu, K., Zou, F., Wang, W., Wang, W., Wu, J., Liu, J., Wang, B., Wang, L., Ren, T., Zhang, S., Yun, C.H., Liu, J., Liu, Q.
Oncotarget
HeaderTransferase
Released2016-08-23
Resolution3.140
CATH Insert Date14 Nov, 2017

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped
G 14 Nov, 2017 Chopped
H 14 Nov, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5gtyA01 10 Dec, 2017 3.30.200.20 Assigned
5gtyA02 10 Dec, 2017 1.10.510.10 Assigned
5gtyB01 10 Dec, 2017 3.30.200.20 Assigned
5gtyB02 10 Dec, 2017 1.10.510.10 Assigned
5gtyC01 10 Dec, 2017 3.30.200.20 Assigned
5gtyC02 10 Dec, 2017 1.10.510.10 Assigned
5gtyD01 10 Dec, 2017 3.30.200.20 Assigned
5gtyD02 10 Dec, 2017 1.10.510.10 Assigned
5gtyE01 10 Dec, 2017 3.30.200.20 Assigned
5gtyE02 10 Dec, 2017 1.10.510.10 Assigned
5gtyF01 10 Dec, 2017 3.30.200.20 Assigned
5gtyF02 10 Dec, 2017 1.10.510.10 Assigned
5gtyG01 10 Dec, 2017 3.30.200.20 Assigned
5gtyG02 10 Dec, 2017 1.10.510.10 Assigned
5gtyH01 10 Dec, 2017 3.30.200.20 Assigned
5gtyH02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor