PDB 5gsa

PDB Links
Overview

PDB Information

PDB	5GSA
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of Qi, W., Zhao, K., Gu, J., Huang, Y., Wang, Y., Zhang, H., Zhang, M., Zhang, J., Yu, Z., Li, L., Teng, L., Chuai, S., Zhang, C., Zhao, M., Chan, H., Chen, Z., Fang, D., Fei, Q., Feng, L., Feng, L., Gao, Y., Ge, H., Ge, X., Li, G., Lingel, A., Lin, Y., Liu, Y., Luo, F., Shi, M., Wang, L., Wang, Z., Yu, Y., Zeng, J., Zeng, C., Zhang, L., Zhang, Q., Zhou, S., Oyang, C., Atadja, P., Li, E. Nat. Chem. Biol.
Header	Transferase/Transferase Inhibitor
Released	2016-08-15
Resolution	2.490
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5gsa

5gsa

PDB 5gsa

Image of CATH 5gsaA

5gsaA

PDB Chain 5gsaA

Image of CATH 5gsaB

5gsaB

PDB Chain 5gsaB

Image of CATH 5gsaC

5gsaC

PDB Chain 5gsaC

Image of CATH 5gsaD

5gsaD

PDB Chain 5gsaD

Image of CATH 5gsaA00

5gsaA00

CATH Domain 5gsaA00

Image of CATH 5gsaB00

5gsaB00

CATH Domain 5gsaB00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped
C	08 May, 2017	Rejected
D	08 May, 2017	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5gsaA00	12 May, 2017	2.130.10.10	Assigned
5gsaB00	12 May, 2017	2.130.10.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
Q15910	EZH2_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase EZH2
O75530	EED_HUMAN	Homo sapiens	Polycomb protein EED