Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.
Blaazer, A.R., Singh, A.K., de Heuvel, E., Edink, E., Orrling, K.M., Veerman, J.J.N., van den Bergh, T., Jansen, C., Balasubramaniam, E., Mooij, W.J., Custers, H., Sijm, M., Tagoe, D.N.A., Kalejaiye, T.D., Munday, J.C., Tenor, H., Matheeussen, A., Wijtmans, M., Siderius, M., de Graaf, C., Maes, L., de Koning, H.P., Bailey, D.S., Sterk, G.J., de Esch, I.J.P., Brown, D.G., Leurs, R.
J. Med. Chem.