PDB Information

PDB5FUE
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceSCHISTOSOMA MANSONI
Primary Citation
Structure-Based Design and Synthesis of Novel Inhibitors Targeting Hdac8 from Schistosoma Mansoni for the Treatment of Schistosomiasis.
Heimburg, T., Chakrabarti, A., Lancelot, J., Marek, M., Melesina, J., Hauser, A.T., Shaik, T.B., Duclaud, S., Robaa, D., Erdmann, F., Schmidt, M., Romier, C., Pierce, R.J., Jung, M., Sippl, W.
J.Med.Chem.
HeaderHydrolase
Released2016-01-26
Resolution2.200
CATH Insert Date10 Apr, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5fueA00 12 May, 2016 3.40.800.20 Assigned
5fueB00 12 May, 2016 3.40.800.20 Assigned
5fueC00 12 May, 2016 3.40.800.20 Assigned
5fueD00 12 May, 2016 3.40.800.20 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8