PDB 5fuc

PDB Information

PDB5FUC
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling.
Adams, R., Burnley, R.J., Valenzano, C.R., Qureshi, O., Doyle, C., Lumb, S., Del Carmen Lopez, M., Griffin, R., McMillan, D., Taylor, R.D., Meier, C., Mori, P., Griffin, L.M., Wernery, U., Kinne, J., Rapecki, S., Baker, T.S., Lawson, A.D., Wright, M., Ettorre, A.
Sci Rep
HeaderImmune System
Released2016-01-25
Resolution2.700
CATH Insert Date07 May, 2017

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped
E 08 May, 2017 Chopped
V 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5fucA00 12 May, 2017 1.20.1250.10 Assigned
5fucB00 11 May, 2017 1.20.1250.10 Assigned
5fucC01 12 May, 2017 2.60.40.10 Assigned
5fucC02 12 May, 2017 2.60.40.10 Assigned
5fucD01 11 May, 2017 2.60.40.10 Assigned
5fucD02 11 May, 2017 2.60.40.10 Assigned
5fucE00 12 May, 2017 2.60.40.10 Assigned
5fucV00 12 May, 2017 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08887 IL6RA_HUMAN Homo sapiens Interleukin-6 receptor subunit alpha
P05231 IL6_HUMAN Homo sapiens Interleukin-6
P08887 IL6RA_HUMAN Homo sapiens Interleukin-6 receptor subunit alpha
P05231 IL6_HUMAN Homo sapiens Interleukin-6