PDB 5fi8

PDB Information

PDB5FI8
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourcePlasmodium falciparum (isolate 3D7)
Primary Citation
Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity.
Kokkonda, S., Deng, X., White, K.L., Coteron, J.M., Marco, M., de Las Heras, L., White, J., El Mazouni, F., Tomchick, D.R., Manjalanagara, K., Rudra, K.R., Chen, G., Morizzi, J., Ryan, E., Kaminsky, W., Leroy, D., Martinez-Martinez, M.S., Jimenez-Diaz, M.B., Bazaga, S.F., Angulo-Barturen, I., Waterson, D., Burrows, J.N., Matthews, D., Charman, S.A., Phillips, M.A., Rathod, P.K.
J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-12-22
Resolution2.320
CATH Insert Date29 May, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5fi8A00 15 Jul, 2016 3.20.20.70 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial