PDB 5fgk

PDB Links
Overview

PDB Information

PDB	5FGK
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19. Mallinger, A., Schiemann, K., Rink, C., Stieber, F., Calderini, M., Crumpler, S., Stubbs, M., Adeniji-Popoola, O., Poeschke, O., Busch, M., Czodrowski, P., Musil, D., Schwarz, D., Ortiz-Ruiz, M.J., Schneider, R., Thai, C., Valenti, M., de Haven Brandon, A., Burke, R., Workman, P., Dale, T., Wienke, D., Clarke, P.A., Esdar, C., Raynaud, F.I., Eccles, S.A., Rohdich, F., Blagg, J. J.Med.Chem.
Header	Transferase
Released	2015-12-20
Resolution	2.360
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5fgk

5fgk

PDB 5fgk

Image of CATH 5fgkA

5fgkA

PDB Chain 5fgkA

Image of CATH 5fgkB

5fgkB

PDB Chain 5fgkB

Image of CATH 5fgkA01

5fgkA01

CATH Domain 5fgkA01

Image of CATH 5fgkA02

5fgkA02

CATH Domain 5fgkA02

Image of CATH 5fgkB01

5fgkB01

CATH Domain 5fgkB01

Image of CATH 5fgkB02

5fgkB02

CATH Domain 5fgkB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5fgkA01	11 May, 2016	3.30.200.20	Assigned
5fgkA02	11 May, 2016	1.10.510.10	Assigned
5fgkB01	11 May, 2016	1.10.472.10	Assigned
5fgkB02	11 May, 2016	1.10.472.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49336	CDK8_HUMAN	Homo sapiens	Cyclin-dependent kinase 8
P24863	CCNC_HUMAN	Homo sapiens	Cyclin-C