PDB Information

PDB5F3H
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceMus musculus
Primary Citation
Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Apgar, J.R., Mader, M., Agostinelli, R., Benard, S., Bialek, P., Johnson, M., Gao, Y., Krebs, M., Owens, J., Parris, K., St Andre, M., Svenson, K., Morris, C., Tchistiakova, L.
Mabs
HeaderSignaling Protein/Immune System
Released2015-12-02
Resolution2.700
CATH Insert Date16 Oct, 2016

PDB Images (33)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped
G 17 Oct, 2016 Chopped
H 17 Oct, 2016 Chopped
I 17 Oct, 2016 Chopped
J 17 Oct, 2016 Chopped
K 17 Oct, 2016 Chopped
L 17 Oct, 2016 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
5f3hA01 22 Oct, 2016 2.60.40.10 Assigned
5f3hA02 22 Oct, 2016 2.60.40.10 Assigned
5f3hB01 22 Oct, 2016 2.60.40.10 Assigned
5f3hB02 22 Oct, 2016 2.60.40.10 Assigned
5f3hC01 21 Oct, 2016 2.60.40.10 Assigned
5f3hC02 21 Oct, 2016 2.60.40.10 Assigned
5f3hD01 21 Oct, 2016 2.60.40.10 Assigned
5f3hD02 21 Oct, 2016 2.60.40.10 Assigned
5f3hE01 22 Oct, 2016 2.60.40.10 Assigned
5f3hE02 22 Oct, 2016 2.60.40.10 Assigned
5f3hF01 22 Oct, 2016 2.60.40.10 Assigned
5f3hF02 22 Oct, 2016 2.60.40.10 Assigned
5f3hG01 22 Oct, 2016 2.60.40.10 Assigned
5f3hG02 22 Oct, 2016 2.60.40.10 Assigned
5f3hH01 22 Oct, 2016 2.60.40.10 Assigned
5f3hH02 22 Oct, 2016 2.60.40.10 Assigned
5f3hI00 30 Nov, 2016 2.10.90.10 Assigned
5f3hJ00 30 Nov, 2016 2.10.90.10 Assigned
5f3hK00 30 Nov, 2016 2.10.90.10 Assigned
5f3hL00 30 Nov, 2016 2.10.90.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O14793 GDF8_HUMAN Homo sapiens Growth/differentiation factor 8
O14793 GDF8_HUMAN Homo sapiens Growth/differentiation factor 8
O14793 GDF8_HUMAN Homo sapiens Growth/differentiation factor 8
O14793 GDF8_HUMAN Homo sapiens Growth/differentiation factor 8