PDB Information

PDB5DWU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors.
Panousis, C., Dhagat, U., Edwards, K.M., Rayzman, V., Hardy, M.P., Braley, H., Gauvreau, G.M., Hercus, T.R., Smith, S., Sehmi, R., McMillan, L., Dottore, M., McClure, B.J., Fabri, L.J., Vairo, G., Lopez, A.F., Parker, M.W., Nash, A.D., Wilson, N.J., Wilson, M.J., Owczarek, C.M.
Mabs
HeaderImmune System
Released2015-09-23
Resolution3.970
CATH Insert Date10 Jan, 2016

PDB Images (11)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Jan, 2016 Domchop review
B 11 Jan, 2016 Chopped
H 11 Jan, 2016 Chopped
L 11 Jan, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5dwuB01 13 Nov, 2017 2.60.40.10 Assigned
5dwuB02 13 Nov, 2017 2.60.40.10 Assigned
5dwuH01 16 Jan, 2016 2.60.40.10 Assigned
5dwuH02 16 Jan, 2016 2.60.40.10 Assigned
5dwuL01 05 Jul, 2016 2.60.40.10 Assigned
5dwuL02 05 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P32927 IL3RB_HUMAN Homo sapiens Cytokine receptor common subunit beta
P32927 IL3RB_HUMAN Homo sapiens Cytokine receptor common subunit beta