PDB 5dtr
PDB Information
| PDB | 5DTR |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket.
Acs Med.Chem.Lett.
|
| Header | Transferase |
| Released | 2015-09-18 |
| Resolution | 2.340 |
| CATH Insert Date | 17 Jul, 2016 |
PDB Prints
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 18 Jul, 2016 | Chopped |
| B | 18 Jul, 2016 | Chopped |
CATH Domains (4)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5dtrA01 | 01 Sep, 2016 | 1.10.260.60 | Assigned |
| 5dtrA02 | 01 Sep, 2016 | 3.40.50.150 | Assigned |
| 5dtrB01 | 01 Sep, 2016 | 1.10.260.60 | Assigned |
| 5dtrB02 | 01 Sep, 2016 | 3.40.50.150 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q8TEK3 | DOT1L_HUMAN | Homo sapiens | Histone-lysine N-methyltransferase, H3 lysine-79 specific |
| Q8TEK3 | DOT1L_HUMAN | Homo sapiens | Histone-lysine N-methyltransferase, H3 lysine-79 specific |