PDB 5dtq

PDB Links
Overview

PDB Information

PDB	5DTQ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket. Scheufler, C., Mobitz, H., Gaul, C., Ragot, C., Be, C., Fernandez, C., Beyer, K.S., Tiedt, R., Stauffer, F. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-09-18
Resolution	2.610
CATH Insert Date	10 Jul, 2016

PDB Images (7)

Image of CATH 5dtq

5dtq

PDB 5dtq

Image of CATH 5dtqA

5dtqA

PDB Chain 5dtqA

Image of CATH 5dtqB

5dtqB

PDB Chain 5dtqB

Image of CATH 5dtqA01

5dtqA01

CATH Domain 5dtqA01

Image of CATH 5dtqA02

5dtqA02

CATH Domain 5dtqA02

Image of CATH 5dtqB01

5dtqB01

CATH Domain 5dtqB01

Image of CATH 5dtqB02

5dtqB02

CATH Domain 5dtqB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dtqA01	14 Jul, 2016	1.10.260.60	Assigned
5dtqA02	14 Jul, 2016	3.40.50.150	Assigned
5dtqB01	14 Jul, 2016	1.10.260.60	Assigned
5dtqB02	14 Jul, 2016	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific