PDB 5dtm

PDB Information

PDB5DTM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket.
Scheufler, C., Mobitz, H., Gaul, C., Ragot, C., Be, C., Fernandez, C., Beyer, K.S., Tiedt, R., Stauffer, F.
Acs Med.Chem.Lett.
HeaderTransferase
Released2015-09-18
Resolution2.200
CATH Insert Date10 Jul, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Jul, 2016 Chopped
B 11 Jul, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5dtmA01 14 Jul, 2016 1.10.260.60 Assigned
5dtmA02 14 Jul, 2016 3.40.50.150 Assigned
5dtmB01 14 Jul, 2016 1.10.260.60 Assigned
5dtmB02 14 Jul, 2016 3.40.50.150 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8TEK3 DOT1L_HUMAN Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3 DOT1L_HUMAN Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-79 specific