PDB 5dry

PDB Links
Overview

PDB Information

PDB	5DRY
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Chen, C., Zhu, H., Stauffer, F., Caravatti, G., Vollmer, S., Machauer, R., Holzer, P., Mobitz, H., Scheufler, C., Klumpp, M., Tiedt, R., Beyer, K.S., Calkins, K., Guthy, D., Kiffe, M., Zhang, J., Gaul, C. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-09-16
Resolution	2.410
CATH Insert Date	17 Jul, 2016

PDB Images (7)

Image of CATH 5dry

5dry

PDB 5dry

Image of CATH 5dryA

5dryA

PDB Chain 5dryA

Image of CATH 5dryB

5dryB

PDB Chain 5dryB

Image of CATH 5dryA01

5dryA01

CATH Domain 5dryA01

Image of CATH 5dryA02

5dryA02

CATH Domain 5dryA02

Image of CATH 5dryB01

5dryB01

CATH Domain 5dryB01

Image of CATH 5dryB02

5dryB02

CATH Domain 5dryB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	18 Jul, 2016	Chopped
B	18 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5dryA01	01 Sep, 2016	1.10.260.60	Assigned
5dryA02	01 Sep, 2016	3.40.50.150	Assigned
5dryB01	01 Sep, 2016	1.10.260.60	Assigned
5dryB02	01 Sep, 2016	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific