PDB 5drt

PDB Links
Overview

PDB Information

PDB	5DRT
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Chen, C., Zhu, H., Stauffer, F., Caravatti, G., Vollmer, S., Machauer, R., Holzer, P., Mobitz, H., Scheufler, C., Klumpp, M., Tiedt, R., Beyer, K.S., Calkins, K., Guthy, D., Kiffe, M., Zhang, J., Gaul, C. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-09-16
Resolution	2.690
CATH Insert Date	10 Jul, 2016

PDB Images (7)

Image of CATH 5drt

5drt

PDB 5drt

Image of CATH 5drtA

5drtA

PDB Chain 5drtA

Image of CATH 5drtB

5drtB

PDB Chain 5drtB

Image of CATH 5drtA01

5drtA01

CATH Domain 5drtA01

Image of CATH 5drtA02

5drtA02

CATH Domain 5drtA02

Image of CATH 5drtB01

5drtB01

CATH Domain 5drtB01

Image of CATH 5drtB02

5drtB02

CATH Domain 5drtB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5drtA01	14 Jul, 2016	1.10.260.60	Assigned
5drtA02	14 Jul, 2016	3.40.50.150	Assigned
5drtB01	14 Jul, 2016	1.10.260.60	Assigned
5drtB02	14 Jul, 2016	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific