PDB Information

PDB5CWZ
MethodX-RAY DIFFRACTION
Host OrganismBaculovirus expression vector pFastBac1-HM
Gene SourceHomo sapiens
Primary Citation
TNIK inhibition abrogates colorectal cancer stemness
Masuda, M., Uno, Y., Ohbayashi, N., Ohata, H., Mimata, A., Kukimoto-Niino, M., Moriyama, H., Kashimoto, S., Inoue, T., Goto, N., Okamoto, K., Shirouzu, M., Sawa, M., Yamada, T.
Nat Commun
HeaderTransferase/Transferase Inhibitor
Released2015-07-28
Resolution2.900
CATH Insert Date07 Aug, 2016

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped
B 08 Aug, 2016 Chopped
C 08 Aug, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5cwzA01 01 Sep, 2016 3.30.200.20 Assigned
5cwzA02 01 Sep, 2016 1.10.510.10 Assigned
5cwzB01 01 Sep, 2016 3.30.200.20 Assigned
5cwzB02 01 Sep, 2016 1.10.510.10 Assigned
5cwzC01 01 Sep, 2016 3.30.200.20 Assigned
5cwzC02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q9UKE5 TNIK_HUMAN Homo sapiens TRAF2 and NCK-interacting protein kinase
Q9UKE5 TNIK_HUMAN Homo sapiens TRAF2 and NCK-interacting protein kinase
Q9UKE5 TNIK_HUMAN Homo sapiens TRAF2 and NCK-interacting protein kinase