PDB 5ctx

PDB Information

PDB5CTX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Mesleh, M.F., Cross, J.B., Zhang, J., Kahmann, J., Andersen, O.A., Barker, J., Cheng, R.K., Felicetti, B., Wood, M., Hadfield, A.T., Scheich, C., Moy, T.I., Yang, Q., Shotwell, J., Nguyen, K., Lippa, B., Dolle, R., Ryan, M.D.
Bioorg.Med.Chem.Lett.
HeaderIsomerase/Isomerase Inhibitor
Released2015-07-24
Resolution1.600
CATH Insert Date10 Apr, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ctxA00 05 May, 2016 3.30.565.10 Assigned
5ctxB00 05 May, 2016 3.30.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0A0K8 GYRB_STAAU Staphylococcus aureus DNA gyrase subunit B
P0A0K8 GYRB_STAAU Staphylococcus aureus DNA gyrase subunit B