PDB 5ctc

PDB Information

PDB5CTC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSaccharomyces cerevisiae
Primary Citation
Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
Kung, D.W., Griffith, D.A., Esler, W.P., Vajdos, F.F., Mathiowetz, A.M., Doran, S.D., Amor, P.A., Bagley, S.W., Banks, T., Cabral, S., Ford, K., Garcia-Irizarry, C.N., Landis, M.S., Loomis, K., McPherson, K., Niosi, M., Rockwell, K.L., Rose, C., Smith, A.C., Southers, J.A., Tapley, S., Tu, M., Valentine, J.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-07-23
Resolution2.700
CATH Insert Date25 Oct, 2015

PDB Images (13)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 26 Oct, 2015 Chopped
B 26 Oct, 2015 Chopped
C 26 Oct, 2015 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
5ctcA01 20 Dec, 2016 3.90.226.10 Assigned
5ctcA02 20 Dec, 2016 2.40.460.10 Assigned
5ctcA03 20 Dec, 2016 3.90.226.10 Assigned
5ctcB01 20 Dec, 2016 3.90.226.10 Assigned
5ctcB02 20 Dec, 2016 2.40.460.10 Assigned
5ctcB03 20 Dec, 2016 3.90.226.10 Assigned
5ctcC01 20 Dec, 2016 3.90.226.10 Assigned
5ctcC02 20 Dec, 2016 2.40.460.10 Assigned
5ctcC03 20 Dec, 2016 3.90.226.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase