PDB 5ctb

PDB Information

PDB5CTB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSaccharomyces cerevisiae
Primary Citation
Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
Kung, D.W., Griffith, D.A., Esler, W.P., Vajdos, F.F., Mathiowetz, A.M., Doran, S.D., Amor, P.A., Bagley, S.W., Banks, T., Cabral, S., Ford, K., Garcia-Irizarry, C.N., Landis, M.S., Loomis, K., McPherson, K., Niosi, M., Rockwell, K.L., Rose, C., Smith, A.C., Southers, J.A., Tapley, S., Tu, M., Valentine, J.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-07-23
Resolution2.400
CATH Insert Date25 Oct, 2015

PDB Images (13)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 26 Oct, 2015 Chopped
B 26 Oct, 2015 Chopped
C 26 Oct, 2015 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
5ctbA01 20 Dec, 2016 3.90.226.10 Assigned
5ctbA02 20 Dec, 2016 2.40.460.10 Assigned
5ctbA03 20 Dec, 2016 3.90.226.10 Assigned
5ctbB01 20 Dec, 2016 3.90.226.10 Assigned
5ctbB02 20 Dec, 2016 2.40.460.10 Assigned
5ctbB03 20 Dec, 2016 3.90.226.10 Assigned
5ctbC01 20 Dec, 2016 3.90.226.10 Assigned
5ctbC02 20 Dec, 2016 2.40.460.10 Assigned
5ctbC03 20 Dec, 2016 3.90.226.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
Q00955 ACAC_YEAST Saccharomyces cerevisiae S288C Acetyl-CoA carboxylase
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