PDB 5ct7

PDB Links
Overview

PDB Information

PDB	5CT7
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma. Williams, T.E., Subramanian, S., Verhagen, J., McBride, C.M., Costales, A., Sung, L., Antonios-McCrea, W., McKenna, M., Louie, A.K., Ramurthy, S., Levine, B., Shafer, C.M., Machajewski, T., Renhowe, P.A., Appleton, B.A., Amiri, P., Chou, J., Stuart, D., Aardalen, K., Poon, D. Acs Med.Chem.Lett.
Header	Transferase
Released	2015-07-23
Resolution	3.170
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 5ct7

5ct7

PDB 5ct7

Image of CATH 5ct7A

5ct7A

PDB Chain 5ct7A

Image of CATH 5ct7B

5ct7B

PDB Chain 5ct7B

Image of CATH 5ct7A01

5ct7A01

CATH Domain 5ct7A01

Image of CATH 5ct7A02

5ct7A02

CATH Domain 5ct7A02

Image of CATH 5ct7B01

5ct7B01

CATH Domain 5ct7B01

Image of CATH 5ct7B02

5ct7B02

CATH Domain 5ct7B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5ct7A01	30 Sep, 2015	3.30.200.20	Assigned
5ct7A02	30 Sep, 2015	1.10.510.10	Assigned
5ct7B01	30 Sep, 2015	3.30.200.20	Assigned
5ct7B02	30 Sep, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf