PDB Information

PDB5CDO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus (strain N315)
Primary Citation
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Chan, P.F., Srikannathasan, V., Huang, J., Cui, H., Fosberry, A.P., Gu, M., Hann, M.M., Hibbs, M., Homes, P., Ingraham, K., Pizzollo, J., Shen, C., Shillings, A.J., Spitzfaden, C.E., Tanner, R., Theobald, A.J., Stavenger, R.A., Bax, B.D., Gwynn, M.N.
Nat Commun
HeaderIsomerase
Released2015-07-04
Resolution3.150
CATH Insert Date27 Dec, 2015

PDB Images (21)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 Dec, 2015 Chopped
B 28 Dec, 2015 Chopped
C 28 Dec, 2015 Chopped
D 28 Dec, 2015 Chopped
E 28 Dec, 2015 Rejected
F 28 Dec, 2015 Rejected
R 28 Dec, 2015 Chopped
S 28 Dec, 2015 Chopped
T 28 Dec, 2015 Chopped
U 28 Dec, 2015 Chopped
V 28 Dec, 2015 Rejected
W 28 Dec, 2015 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5cdoA00 05 Jan, 2016 Holding pen
5cdoB01 23 Jan, 2017 Holding pen
5cdoC00 05 Jan, 2016 Holding pen
5cdoD01 23 Jan, 2017 Holding pen
5cdoR00 05 Jan, 2016 Holding pen
5cdoS01 23 Jan, 2017 Holding pen
5cdoT00 05 Jan, 2016 Holding pen
5cdoU01 23 Jan, 2017 Holding pen

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
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