PDB Information

PDB5C23
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Kumar, A., Aguirre, J.D., Condos, T.E., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
Embo J.
HeaderLigase
Released2015-06-15
Resolution2.370
CATH Insert Date16 Aug, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5c23A01 29 Nov, 2016 3.10.20.90 Assigned
5c23A02 29 Nov, 2016 Holding pen
5c23B01 30 Nov, 2016 3.10.20.90 Assigned
5c23B02 30 Nov, 2016 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60260 PRKN_HUMAN Homo sapiens E3 ubiquitin-protein ligase parkin
O60260 PRKN_HUMAN Homo sapiens E3 ubiquitin-protein ligase parkin