PDB 5c08

PDB Information

PDB5C08
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Cole, D.K., Bulek, A.M., Dolton, G., Schauenberg, A.J., Szomolay, B., Rittase, W., Trimby, A., Jothikumar, P., Fuller, A., Skowera, A., Rossjohn, J., Zhu, C., Miles, J.J., Peakman, M., Wooldridge, L., Rizkallah, P.J., Sewell, A.K.
J.Clin.Invest.
HeaderImmune System
Released2015-06-12
Resolution2.330
CATH Insert Date15 May, 2016

PDB Images (25)

PDB Prints

PDB Chains (10)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped
C 16 May, 2016 Rejected
D 16 May, 2016 Chopped
E 16 May, 2016 Chopped
F 16 May, 2016 Chopped
G 16 May, 2016 Chopped
H 16 May, 2016 Rejected
I 16 May, 2016 Chopped
J 16 May, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5c08A01 20 Oct, 2016 3.30.500.10 Assigned
5c08A02 20 Oct, 2016 2.60.40.10 Assigned
5c08B00 13 Jul, 2016 2.60.40.10 Assigned
5c08D01 13 Jul, 2016 2.60.40.10 Assigned
5c08D02 13 Jul, 2016 2.60.40.10 Assigned
5c08E01 13 Jul, 2016 2.60.40.10 Assigned
5c08E02 13 Jul, 2016 2.60.40.10 Assigned
5c08F01 20 Oct, 2016 3.30.500.10 Assigned
5c08F02 20 Oct, 2016 2.60.40.10 Assigned
5c08G00 13 Jul, 2016 2.60.40.10 Assigned
5c08I01 13 Jul, 2016 2.60.40.10 Assigned
5c08I02 13 Jul, 2016 2.60.40.10 Assigned
5c08J01 13 Jul, 2016 2.60.40.10 Assigned
5c08J02 13 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4