PDB 5aqp

PDB Information

PDB5AQP
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution2.080
CATH Insert Date16 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqpA01 25 Oct, 2016 3.30.420.40 Assigned
5aqpA02 25 Oct, 2016 3.30.30.30 Assigned
5aqpA03 25 Oct, 2016 3.30.420.40 Assigned
5aqpA04 25 Oct, 2016 3.90.640.10 Assigned
5aqpB00 22 Oct, 2016 1.20.58.120 Assigned
5aqpC01 25 Oct, 2016 3.30.420.40 Assigned
5aqpC02 25 Oct, 2016 3.30.30.30 Assigned
5aqpC03 25 Oct, 2016 3.30.420.40 Assigned
5aqpC04 25 Oct, 2016 3.90.640.10 Assigned
5aqpD00 22 Oct, 2016 1.20.58.120 Assigned
5aqpE01 25 Oct, 2016 3.30.420.40 Assigned
5aqpE02 25 Oct, 2016 3.30.30.30 Assigned
5aqpE03 25 Oct, 2016 3.30.420.40 Assigned
5aqpE04 25 Oct, 2016 3.90.640.10 Assigned
5aqpF00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein