PDB 5aqo

PDB Information

PDB5AQO
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution2.120
CATH Insert Date16 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqoA01 25 Oct, 2016 3.30.420.40 Assigned
5aqoA02 25 Oct, 2016 3.30.30.30 Assigned
5aqoA03 25 Oct, 2016 3.30.420.40 Assigned
5aqoA04 25 Oct, 2016 3.90.640.10 Assigned
5aqoB00 22 Oct, 2016 1.20.58.120 Assigned
5aqoC01 25 Oct, 2016 3.30.420.40 Assigned
5aqoC02 25 Oct, 2016 3.30.30.30 Assigned
5aqoC03 25 Oct, 2016 3.30.420.40 Assigned
5aqoC04 25 Oct, 2016 3.90.640.10 Assigned
5aqoD00 22 Oct, 2016 1.20.58.120 Assigned
5aqoE01 25 Oct, 2016 3.30.420.40 Assigned
5aqoE02 25 Oct, 2016 3.30.30.30 Assigned
5aqoE03 25 Oct, 2016 3.30.420.40 Assigned
5aqoE04 25 Oct, 2016 3.90.640.10 Assigned
5aqoF00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein