PDB 5aqj

PDB Information

PDB5AQJ
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution1.960
CATH Insert Date16 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqjA01 25 Oct, 2016 3.30.420.40 Assigned
5aqjA02 25 Oct, 2016 3.30.30.30 Assigned
5aqjA03 25 Oct, 2016 3.30.420.40 Assigned
5aqjA04 25 Oct, 2016 3.90.640.10 Assigned
5aqjB00 22 Oct, 2016 1.20.58.120 Assigned
5aqjC01 25 Oct, 2016 3.30.420.40 Assigned
5aqjC02 25 Oct, 2016 3.30.30.30 Assigned
5aqjC03 25 Oct, 2016 3.30.420.40 Assigned
5aqjC04 25 Oct, 2016 3.90.640.10 Assigned
5aqjD00 21 Oct, 2016 1.20.58.120 Assigned
5aqjE01 25 Oct, 2016 3.30.420.40 Assigned
5aqjE02 25 Oct, 2016 3.30.30.30 Assigned
5aqjE03 25 Oct, 2016 3.30.420.40 Assigned
5aqjE04 25 Oct, 2016 3.90.640.10 Assigned
5aqjF00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1